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Diffusion-Weighted Magnetic Resonance Imaging:Detection of Ischemic Injury 39 Minutes After Onset in a Stroke Patient
Ann Neurol 45:794-797, Yoneda,Y.,et al, 1999
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Article Abstract
A neurologist witnessed the in-hospital onset of an ischemic stroke in a 71-year-old right-handed male who suddenly developed global aphasia and right hemiplegia. Diffusion-weighted magnetic resonance imaging (DWI) 39 minutes after the ict us demonstrated high signals in the left internal carotid artery territory. T1- and T2- weighted images failed to detect this change. Magnetic resonance angiography showed occlusions in branches of the left anterior and middle cerebral arteries and an a theromatous stenotic lesion in the ipsilateral proximal internal carotid artery. The patient was treated with intravenous heparin and low molecular dextran solution. Repeated magnetic resonance imagings identified an infarction slightly smaller than the abnormality demonstrated by the initial DWI. DWI detects hyperacute ischemic injury within 1 hour of symptom onset in human ischemic stroke.
 
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cerebrovascular accident
cerebrovascular disease,noninvasive evaluation of
MRI
MRI,abnormal
MRI,cerebrovascular disease
MRI,diffusion weighted
MRI,early changes in CVA
MRI,false negative

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